Menopause Effects on Cortico-reticular Functioning

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age50-59
SponsorUniversity of Jyvaskyla

About this trial

Post-menopausal women who request to begin hormone-replacement therapy (HRT) are directed to the research team. The participants are tested before beginning HRT, after two months of HRT, and five months of HRT. Tests include strength performance, central nervous system functioning, body composition, resting metabolic rate, and vascular screening. The participants are provided a 12-week training intervention (2 x strength, 2 x endurance per week) that can be voluntarily followed between tests at month 2 and 5. Compliance with the training program is recorded. A minimum of 15 participants are needed a priori, but the investigators aim to recruit and test 20 women.

Eligibility criteria

Qualifiers

at least 6 months since their last period but no more than being 5 years post-menopausal

basal follicular-stimulating hormone concentration > 30 IU/L (confirmed post-recruitment)

willing to start combined hormonal treatment

womb and ovaries intact with normal functioning throughout reproductive age

Disqualifiers

classified as excessively obese via BMI assessment (i.e., >35 kg/m2)

intra-uterine device usage during transition to menopause

cardiovascular or skeletomuscular disease preventing strenuous physical activity

smoker

Trial design

Treatments tested in this trial

  • Physical training

Treatment groups

20 Participants
are divided into 1 treatment group

Sponsors and collaborators