Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHeinrich-Heine University, Duesseldorf
About this trial
Women and men show marked differences in cardiovascular risk profile and outcome. Women experience fewer cardiovascular events than men before menopause, but this relationship seems to reverse at menopause. These disparities are probably due to hormonal factors, especially the female sex hormone estrogen seems to have a protective influence on the development of atherosclerotic plaques premenopausal.
The underlying mechanisms of the effect of estrogens on the vessel wall are still insufficiently investigated. In this study, menopause related effects on leukocyte distribution and function as well on platelets and their aggregational response will be evaluated.
Eligibility criteria
Qualifiers
Age > 18 years
Male, female, diverse patients with current treatment in the Department of Cardiology, Pneumology and Angiology.
Persons who are able to understand and follow the instructions of the study staff
Written informed consent
Disqualifiers
Age < 18 years
Lack of written consent to participate in the study
coagulation disorders
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Source ClinicalTrials.gov