Metabolic and Functional Consequences of Aging in Health and Disease
ConditionAging
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50+
SponsorTexas A&M University
About this trial
Considerable heterogeneity in the aging population has been observed. The exceptional longevity of individuals reaching 100 years old, so-called centenarians may be an example of life-long healthy aging, or added years may be spent in poor health with decreased physical and cognitive functioning. Current knowledge of the aging experience and the trajectories of physical and cognitive decline across various age groups are not well-understood, yet crucial to prevent spending added years in disease. Hence, the study objective is to develop the metabolic profile associated with aging-related disorders measured as the incidence of impaired functional capacity, cognitive function, and/or well-being.
Eligibility criteria
Qualifiers
Stable body-weight (± 5%) for the past 3 months
Subject is judged to be in satisfactory health based on medical history, physical examination, and laboratory screening evaluations.
Ability to walk, sit down and stand up independently or with walking mobility aids
Ability to lie in a supine or elevated position for up to 3 hours
Disqualifiers
Insulin dependent diabetes mellitus
Established diagnosis of malignancy
History of untreated metabolic diseases including hepatic or renal disorder
Presence of acute illness or metabolically unstable chronic illness
Trial design
Treatments tested in this trial
- Stable tracer infusion in a postabsorptive state
Treatment groups
100 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov