Metabolic Control of Aging and Disease - the MetAGE Deep Phenotyping Cohort
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThomas Scherer
About this trial
The goal of this prospective observational study is to identify and validate blood based aging biomarkers in relation to cardiometabolic phenotypes of young and old, female and male subjects with or without obesity.
The main question is to gain insights into the interaction of obesity related metabolic alteration and aging, and the relevance of loss of metabolic control in the development of age-related diseases in order to build a foundation for targeted drug- and lifestyle interventions in future studies.
Eligibility criteria
Qualifiers
Age 18 - 35 years
Body mass index (BMI) ≥ 18.5 and ≤ 24.9 kg/m2 (≥ 12 months)
Age 18 - 35 years
BMI ≥ 28kg/m2 (≥ 12 months)
Disqualifiers
Highly physical active (i.e. > 5 times sporting activity / week with moderate to high intensity [heart rate 140 - 200bpm])
Special diets (i.e. ketogenic diet and time-restricted eating)
Clinically significant metabolic or endocrine disorders
Claustrophobia
Trial design
Treatments tested in this trial
- comprehensive metabolic phenotyping
Treatment groups
650 Participants
are divided into 5 treatment groupsSponsors and collaborators
Thomas Scherer
Lead sponsor
Medical University of Vienna
Sponsor institution
Medical University of Graz
Collaborator
University of Graz
Collaborator
Source ClinicalTrials.gov