The primary goal of this randomized controlled trial is to compare the effectiveness of two transdiagnostic psychological treatments, Metacognitive Therapy (MCT) and the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP), for patients with complex anxiety.
Age 18 years or above
Ability to read and speak Swedish
A principal diagnosis of post-traumatic stress disorder, generalized anxiety disorder, social anxiety disorder, or panic disorder
At least one additional comorbid diagnosis (one of the above diagnoses, or obsessive-compulsive disorder, or major depressive disorder)
Current diagnosis of psychosis, bipolar disorder or moderate to severe substance use disorder
Medium to high suicide risk
Psychiatric, somatic or social problems that require primary intervention other than the treatments offered in the study
Concurrent psychological treatment
Karolinska Institutet
Lead sponsor
Region Stockholm
Collaborator