Methacholine Challenge Test in School Children With/Without Asthma RISKA

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age7-15
SponsorHelsinki University Central Hospital

About this trial

The study includes a pre-study telephone interview with healthy controls to assess their eligibility for participation. During the study visit, a background information form and an asthma questionnaire are completed. At the study visit, a methacholine challenge test measuring airway hyperresponsiveness and an exhaled nitric oxide measurement are performed. The effect of medication intensification in asthma patients is further assessed through a telephone interview 1-2 months after the medication adjustment.

Eligibility criteria

Qualifiers

• Aged 7-15 years, both sexes

No diagnosis of asthma in childhood

No inhaled asthma medication during the previous 2 years

No wheezing or shortness of breath during the previous 2 years

Disqualifiers

• Premature birth before 32 gestational weeks

Other chronic cardiopulmonary or neurological conditions affecting airways (excluding asthma)

Severe underlying illness such as malignancy

Beta-blocker medication

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

260 Participants
are grouped into 3 trial groups