About this trial
The study includes a pre-study telephone interview with healthy controls to assess their eligibility for participation. During the study visit, a background information form and an asthma questionnaire are completed. At the study visit, a methacholine challenge test measuring airway hyperresponsiveness and an exhaled nitric oxide measurement are performed. The effect of medication intensification in asthma patients is further assessed through a telephone interview 1-2 months after the medication adjustment.
Eligibility criteria
Qualifiers
• Aged 7-15 years, both sexes
No diagnosis of asthma in childhood
No inhaled asthma medication during the previous 2 years
No wheezing or shortness of breath during the previous 2 years
Disqualifiers
• Premature birth before 32 gestational weeks
Other chronic cardiopulmonary or neurological conditions affecting airways (excluding asthma)
Severe underlying illness such as malignancy
Beta-blocker medication
Trial design
Treatments tested in this trial
- Not listed