Proof of concept: Pilot Study
A Pilot, proof of concept, observational study with a long-term goal to develop a minimally invasive wearable Remote Medication Monitor (RMM) that provides continuous, real-time data on methadone levels in interstitial fluid (ISF). An RMM could be used as a medication adherence monitor and would allow for the physician, counselor, patient, or family member to remotely verify that a physician-prescribed dose has been taken.
Age 18-70
A prescription for methadone at a dose of 10mg or more for at least one week.
Taking methadone as prescribed during the last 4 days before consent to participate in the study.
Age <18 or >70
A condition preventing or complicating ISF collection
dermatological (skin) condition
immunodeficiency