Microflow3D - Non-invasive Mapping of Coronary Arteries and the Cerebral Vascular Network Using 3D Ultrasound Localization Microscopy in Patients With Atherosclerosis Prior to Carotid Endarterectomy Surgery

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorFrench Cardiology Society

About this trial

There is a need to simplify the assessment of coronary and cerebral vascular networks in patients selected for carotid endarterectomy in order to prevent potential complications during and after surgery. A non-invasive, non-ionizing 3 dimension mapping of these networks would provide a remarkable benefit for patients.

Eligibility criteria

Qualifiers

Patients with asymptomatic carotid stenosis, without recent stroke, and scheduled for carotid endarterectomy within the next 30 days.

Age ≥ 18 years.

Beneficiary of a social security system or equivalent coverage.

Signed informed consent.

Disqualifiers

Contraindication to the use of the ultrasound contrast agent SonoVue®: known hypersensitivity to the active substance or to any of the following excipients: Macrogol 4000; Distearoylphosphatidylcholine; Sodium dipalmitoylphosphatidylglycerol; Palmitic acid.

Allergy to ultrasound gel.

Refusal or inability (linguistic or psychological) to sign the informed consent form.

Subject to legal protection measures, such as guardianship (in accordance with Article L1122-2 of the French Public Health Code).

Trial design

Treatments tested in this trial

  • Ultrasound localization microscopy, circle of Willis
  • Ultrasound localization microscopy, coronary arteries

Treatment groups

37 Participants
are divided into 1 treatment group

Sponsors and collaborators