Microneedling With Platelet Rich Plasma Versus Microneedling Alone For Gingival Depigmentation
ConditionGingival Pigmentation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCairo University
About this trial
To evaluate the usage of microneedling with platelet rich plasma as a gingival depigmentation method in comparison to microneedling alone for pigment intensity reduction.
Pre-operative preparation phase includes ultrasonic scaling and oral hygiene instructions for all patients. Eligible patients will be randomly allocated into two groups.
Clinical photographs: Clinical photographs will be taken at baseline, 1 and 6 months postoperatively.
Intervention Group (Group A): Microneedling will be done with application of Platelet Rich Plasma for depigmentation.
Control Group (Group B): microneedling will be done alone for depigmentation.
Eligibility criteria
Qualifiers
• Patients exhibiting melanin hyperpigmentation in the anterior region of the upper or lower gingiva.
Age ≥ 18 year old.
Patients should be free from any systemic diseases according to modified Cornell Medical index (Abramson 1966).
Non- smokers
Disqualifiers
• Fully edentulous patients.
Patients with endocrine disorders causing hyperpigmentation or drug induced gingival pigmentation. (Sreeja, Ramakrishnan et al. 2015)
Pregnant or lactating females.
Trial design
Treatments tested in this trial
- Microneedling will be done with application of Platelet Rich Plasma for depigmentation.
- Microneedling alone for Gingival Depigmentation.
Treatment groups
32 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov