Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars

ConditionsScarsInsulin
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-60
SponsorAlexandria University

About this trial

Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars. In addition, a lack of inclusion of a control group instead of comparing topical preparations with insulin was also a limitation to these studies. A control group consisting of microneedling alone would have served as a better comparison in order to determine whether the effects of microneedling are augmented by topical protein-rich preparations.

Eligibility criteria

Qualifiers

Patients aged 12 to 60 years

Atrophic scars (traumatic or surgical)

Completely healed scars

Disqualifiers

Patients with a tendency or history of hypertrophic or keloidal scars

Patients who received treatment for their scar in the past 3 months

Diabetic patients or those with a history of Dysglycemia

Pregnant, or lactating females

Trial design

Treatments tested in this trial

  • Microneedling with topical application of regular insulin
  • Microneedling with topical application of saline

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators