About this trial
Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars. In addition, a lack of inclusion of a control group instead of comparing topical preparations with insulin was also a limitation to these studies. A control group consisting of microneedling alone would have served as a better comparison in order to determine whether the effects of microneedling are augmented by topical protein-rich preparations.
Eligibility criteria
Qualifiers
Patients aged 12 to 60 years
Atrophic scars (traumatic or surgical)
Completely healed scars
Disqualifiers
Patients with a tendency or history of hypertrophic or keloidal scars
Patients who received treatment for their scar in the past 3 months
Diabetic patients or those with a history of Dysglycemia
Pregnant, or lactating females
Trial design
Treatments tested in this trial
- Microneedling with topical application of regular insulin
- Microneedling with topical application of saline