MicroRNA Regulation of Chronic Inflammation During Aging
ConditionChronic Inflammation
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Utah
About this trial
This is an observational study enrolling healthy individuals aged 18-35 and 65y and older to determine the health of immune cells in the blood and how these cells create inflammation and effect health as we age. It is hoped that once the nature of this relationship has been discovered we can more effectively design therapies to reduce this inflammation.
The enrollment goal is 40 participants. The study will occur over the course of 1 month which will include a screening visit and a second visit where the participants will undergo an oral glucose tolerance test, blood draws and leg strength \& exercise tests.
Eligibility criteria
Qualifiers
Age between 18 - 35y; 65y and older
BMI: <30 kg/m2
Ability to sign informed consent
For older participant group: Clinical Frailty Scale score < 3 and Mini-Cog score > 3
Disqualifiers
History of cardiovascular disease (e.g., CHF, CAD, MI, CVA)
History of endocrine or metabolic disease such as hypo/hyperthyroidism and diabetes (Treated hypo/hyperthyroid for at least 6 months will be permitted)
History of kidney disease or failure (CKD > stage 4)
History of vascular disease
Trial design
Treatments tested in this trial
- Not listed
Trial groups
40 Participants
are grouped into 2 trial groupsSponsors and collaborators
Source ClinicalTrials.gov