Minimally INvasive Colon Cancer Surgery Through IMmunomics and Optical Mapping of the Sentinel Lymph Node.
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital, Ghent
About this trial
The project investigates the feasibility of laparoscopic fluorescent imaging for the intraoperative detection of the sentinel lymph node (SLN) in colon cancer patients. In addition, the topology of immunological and microenvironmental changes in normal and invaded lymph nodes (LN's) will be correlated to the LN location (anatomical mapping).
Eligibility criteria
Qualifiers
Tumor type: proven adenocarcinoma of the colon
Extent of disease (AJCC 7th edition): clinically node negative (stage II) non-metastatic colon cancer
Locally resectable disease
Adequate mental faculty, allowing to understand the proposed treatment protocol and provide informed consent
Disqualifiers
Node positive and/or metastatic disease
Locally unresectable disease
Medically unfit patients (Karnofsky index < 70%)
Allergies to any of the procedural substances (allergy to iodides, hypersensitivity to products containing human albumin)
Trial design
Treatments tested in this trial
- ICG-nanocoll (indocyanine green coupled to the human albumin colloidal particle nanocoll)
Treatment groups
70 Participants
are divided into 1 treatment groupSponsors and collaborators
University Hospital, Ghent
Lead sponsor
Kom Op Tegen Kanker
Collaborator
Source ClinicalTrials.gov