Minimally-Invasive Non-Surgical Therapy of Peri-Implantitis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSt. Anne's University Hospital Brno, Czech Republic
About this trial
This multicenter, single-masked randomized controlled clinical trial evaluates the effectiveness of minimally-invasive non-surgical therapy (MINST) compared with standard non-surgical peri-implant therapy (NSPT) in patients diagnosed with peri-implantitis. The study investigates clinical outcomes, radiographic bone levels, patient-reported outcomes, and treatment time over 12 months.
Eligibility criteria
Qualifiers
Age ≥18
Peri-implantitis diagnosis (PPD >6 mm, BOP+, bone loss ≥3 mm)
Accessible implant surface without removing suprastructure
FMPS <30%, FMBS <30-35%
Disqualifiers
Antibiotics in last 3 months
Pregnancy/lactation
Uncontrolled diabetes (HbA1c ≥7)
Long-term SPIC (>2 years)
Trial design
Treatments tested in this trial
- Non-Surgical Peri-implant Therapy (NSPT)
- Minimally-Invasive Non-Surgical Therapy (MINST)
Treatment groups
106 Participants
are divided into 2 treatment groupsSponsors and collaborators
St. Anne's University Hospital Brno, Czech Republic
Lead sponsor
King's College London
Collaborator
Source ClinicalTrials.gov