Mitochondrial Function in Peripheral Blood Mononuclear Cells, Muscle, and Skin of Long COVID Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversitair Ziekenhuis Brussel
About this trial
Mitochondria are structures inside cells that are responsible for producing energy from nutrients through a series of steps, using oxygen. To have an idea of how well the mitochondria can produce energy, we can measure how much oxygen they use. The goal of this study is to:
1. To compare the oxygen use between people with long COVID and people who completely recovered after COVID-19, using three techniques that measure the oxygen use in blood cells, on the skin and in the muscle 2. To test how similar these three techniques are in measuring the oxygen used in the three different tissues
Participants will:
* Complete surveys, * Wear an activity tracker (7 days), * Undergo several non-invasive tests, and * Donate a blood sample The study will take place in UZ Brussel hospital and will take 2 study visits, approximately 7 days apart.
Eligibility criteria
Qualifiers
Long COVID diagnosis, based on the WHO definition;
Presence of long COVID symptoms for a minimum of 6 months.
History of confirmed or documented SARS-CoV-2 infection.
Adult (≥18 years of age).
Disqualifiers
Pre-existing chronic diseases potentially affecting the functional status scale.
Treatment with metabolism altering drugs.
> 10 standard units of alcohol (10 grams of alcohol/glass) per week.
Unable to understand oral and written instructions in Dutch, French or English.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
54 Participants
are grouped into 2 trial groupsSponsors and collaborators
Source ClinicalTrials.gov