Mobile Technology to Measure Knee Health in Osteoarthritis
ConditionOsteoarthritis, Knee
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age30+
SponsorVA Office of Research and Development
About this trial
Veterans face a high prevalence of knee osteoarthritis (OA), but current diagnostic methods often miss early stages when interventions are more effective. This project will evaluate smartphone-based motion capture via OpenCap to measure joint mechanics in knee OA patients during functional activities, comparing its performance to a conventional motion capture system, patient-reported symptoms, and knee joint structure. The findings will have the potential to enable clinicians to trial OpenCap in its current form, provide insights into tracking joint health, and guide refinements to advance toward earlier diagnosis of knee OA by complementing symptom assessments with measures of joint mechanics.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Veteran and non-Veterans
males and females
diagnosed with early knee osteoarthritis
qualified for and participated in the Precision Assessment of Platelet Rich Plasma for Joint Preservation study (ClinicalTrials.gov ID: NCT03460236)
Disqualifiers
symptomatic OA in joints other than the knee in the lower body
joint replacement
rheumatic disease
BMI > 35 kg/m²
Trial population
Individuals who were diagnosed with early knee osteoarthritis and had a history of being elected to receive injection treatment
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
47 Participants
are grouped into 1 trial groupGroup A: Knee OA
Trial outcomes
Primary outcomes
1
Knee flexion angle
Knee flexion angle extracted from functional activities (e.g., walking, chair-to-stand)
Time frame
Baseline and Week 1Secondary outcomes
1
Knee flexion moment
Knee flexion moment estimated from functional activities (e.g., walking, chair-to-stand)
Time frame
Baseline and Week 1Other outcomes
1
Western Ontario and McMaster Universities Osteoarthritis Index (Transformed)
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores will be calculated from answers to the Knee Injury and Osteoarthritis Outcome Score questionnaire, including domains of Pain, Stiffness, and Function. WOMAC scores will be transformed to a scale of 0-100, with higher scores indicating fewer symptoms.
Time frame
Baseline and Week 12
Duration of 40-meter fast walk test
Duration in seconds to complete 40-meter fast walk test
Time frame
Baseline or Week 13
Repetitions for 30-second chair-to-stand test
The number of repetitions of chair-to-stand performed during 30-second
Time frame
Baseline or Week 1Sponsors and contacts
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Source ClinicalTrials.gov