Modeling and Closed-loop Control of Depth of Anaesthesia

ConditionThe Focus is to Develop a Closed-loop Control System for Anaesthesia in Vitroretinal Surgery, Surgery Due to Expansive Processes in Head, and Long-term Sedation

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age20-70

SponsorUniversity of Ljubljana

About this trial

The study evaluates the effect of anaesthetic agents to depth of anaesthesia. An improved PK-PD model wil be developed that will provide the basis for understanding the mechanisms, simulating various scenarios and developing algorithms for better and safer administration of anaesthetic agents.

Eligibility criteria

Qualifiers

patients having vitroretinal surgery in general anaesthesia

patients having brain surgery in general anaesthesia

patients needing sedation in ICU

ASA 1-3

Disqualifiers

ASA > 3

BMI > 35

drug addicts

patients taking psychotropic medicines

Trial design

Treatments tested in this trial

Propofol

Treatment groups

50 Participants

are divided into 1 treatment group

Sponsors and collaborators

University of Ljubljana

Lead sponsor

Source ClinicalTrials.gov