MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-17
SponsorOelisoa Andriankaja
About this trial
The goal of this clinical trial is to assess whether adjunctive dental cleaning can enhance the effects of semaglutide in children with obesity. The main question\[s\] it aims to answer \[is/are\]:
if dental cleaning will improve both oral health and metabolic outcomes beyond the effects of semaglutide alone.
Participants will receive either dental cleaning and oral hygiene instruction or oral hygiene instruction alone.
Eligibility criteria
Qualifiers
participants from the ongoing Mitigation of Cardiovascular Disease Risks in Children with Extreme Obesity (MODERN) study (NCT06967389)
Class 2 or 3 obesity (BMI =120% of the 95th percentile for age and sex)
Disqualifiers
Same exclusion as parent study.
Planning to receive or complete dental services during the 12-month course of the study
Ongoing orthodontic treatment
Use of any anti-inflammatory medication (other than steroids) within 1 month prior to enrollment
Trial design
Treatments tested in this trial
- Dental Cleaning and Oral Hygiene Instruction (OHI)
- Oral Hygiene Instruction (OHI)
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Oelisoa Andriankaja
Lead sponsor
University of Kentucky
Sponsor institution
Source ClinicalTrials.gov