Modulating Movement Intention Via Cortical Stimulation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorNYU Langone Health

About this trial

The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies. These results could provide preliminary data for subsequent studies evaluating local and global efficacy of plasticity-inducing treatments for PMD symptoms.

Eligibility criteria

Qualifiers

Fluent in English

Diagnosis of PMD/PNES confirmed by a neurologist with expertise in movement disorders.

Per the treating neurologist, subject is unlikely to require treatment and/or dosage changes for 3-6 months following screening

Disqualifiers

Any history of a significant neurological disorder, which may interfere with the interpretation of study data, as determined by the PI

Chronic or progressive medical condition

Any history of traumatic brain injury or significant head trauma

Currently meets criteria for substance abuse or dependence

Trial design

Treatments tested in this trial

  • Sham TMS3 stimulation
  • rTMS of left or right angular gyrus (AG) or frontal cortex (FC)
  • Anodal tDCS of left or right AG or FC

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators