Modulation of Brain Oscillations Underlying Working Memory

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorMassachusetts General Hospital

About this trial

This study will use novel transcranial alternating current stimulation (tACS) protocols and electroencephalography (EEG) to modulate and measure brain oscillations that underlie working memory. tACS is a noninvasive method used to modulate the timing and patterns of brain rhythms via weak electric currents passed through electrodes on the scalp.

Eligibility criteria

Qualifiers

Able to provide informed consent

Fluent in English.

Disqualifiers

History of a neurological/psychiatric disorder

Current use of psychotropic medications

Current use of substances and drugs that were shown to affect tES (transcranial electrical stimulation) efficacy (dopamine altering drugs, nicotine, NMDA (N-methyl-D-aspartate) antagonists/agonists, sodium/calcium channel blockers, norepinephrine reuptake inhibitors, GABAergic modulators and selective serotonin reuptake inhibitors)

Contraindications for tACS (e.g., history of seizures, metallic implants in the head or neck, implanted brain stimulators, vagus nerve stimulators, pacemakers, pregnancy)

Trial design

Treatments tested in this trial

  • Active tACS
  • Placebo tACS

Treatment groups

32 Participants
are divided into 4 treatment groups

Sponsors and collaborators