Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorBoston Children's Hospital
About this trial
The goal of this study is to discover new genetic causes of infantile epilepsies and evaluate the impact of these discoveries on infants with epilepsy and their families.
Eligibility criteria
Qualifiers
Seizure onset at less than 12 months of age
Enrollment within 6 weeks of seizure-related presentation
Patient at Boston Children's Hospital
Disqualifiers
Simple febrile seizures
Acute provoked seizures (e.g., due to sepsis, hemorrhage, electrolyte abnormality, cerebral infarction, hypoxic ischemic encephalopathy, non-accidental injury)
Genetic or acquired cause of epilepsy already identified, including brain magnetic resonance imaging findings consistent with a specific genetic etiology (e.g., tuberous sclerosis complex)
Deceased prior to enrollment
Trial design
Treatments tested in this trial
- Genomic Sequencing
Treatment groups
600 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov