Molecular Indicators of Systematic Fitness
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorVO Health, Inc.
About this trial
The goal of this study is to characterize associations between cardiorespiratory fitness, as measured by VO₂max/VO₂peak, and blood-based molecular measurements in adults. This is an observational study where research staff measures VO₂max/VO₂peak and collects fasted, resting blood samples on the same day. The main questions it aims to answer are:
1. Can a multi-analyte blood panel accurately predict directly measured VO₂max/VO₂peak? 2. How do these blood-based features vary across age, sex, and self-reported or documented physical activity profiles? 3. Are the predictor analytes able to capture changes in VO₂max/VO₂peak caused by a self-directed intervention (e.g., training for a marathon)? 4. What is the analytic reliability of the predictor biomarkers?
Eligibility criteria
Qualifiers
Be ≥18 years old
Be able to understand and provide informed consent (English; additional languages may be added via amendment with translated materials)
Be willing to complete VO₂max testing, blood draw, and questionnaires.
Be able to safely perform maximal/symptom-limited exercise testing as determined by: PAR-Q+ screening and investigator review (included as an attachment) and resting vitals screening (heart rate)
Disqualifiers
Conditions that, in the investigator's judgment, or a medical doctor, makes maximal exercise testing unsafe (e.g., unstable cardiovascular symptoms)
Contraindications or unwillingness to undergo venipuncture
Acute illness (fever, significant respiratory illness) at the time of testing
Failure to comply with procedures.
Trial design
Treatments tested in this trial
- There is no intervention.
Treatment groups
No treatment groups listed
Sponsors and collaborators
Source ClinicalTrials.gov