Molecular Services and EMR-Lab Integration Application (ELIA) for Reducing Healthcare Disparities in Cancer Patients

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorBien-Willner Physicians Group PA

About this trial

The goal of this observational study is to measure and try to reduce leakage in precision medicine care in the community cancer clinic. The goal of precision medicine is to identify the best possible therapy the the patient based on the biology of the tumor. Leakage is defined as a failure or inefficiency of the system that leads to dropped or lost testing, reporting or action (including drug selection). It has been observed that there are healthcare disparities in the community setting compared to academic medical centers, particularly in the use of precision medicine. The main questions the study aims to answer are:

* How much leakage occurs in the use of precision medicine in the community setting? * Can we reduce leakage by providing access to better tools and services typically found in the academic medical centers? Participants will not be directly impacted and will receive standard of care. Measurements will be made of how often physicians select the appropriate test for patients, and how often they select the most appropriate therapy for their patients before and after the implementation of tools created to reduce leakage.

We hope to reduce leakage in with the use of advanced tools and services, and use this study as a model to improve healthcare in the community cancer setting.

Eligibility criteria

Qualifiers

newly diagnosed or change in status Advanced Cancer patient (recurrent, refractory, metastatic, or high grade)

Cancer patient for whom genomic testing (comprehensive genomic profile (CGP)) is recommended by relevant guidelines

Disqualifiers

Patient does not seek additional treatment

Patient younger than 18 years

Treatment provided at a tertiary medical center

CGP testing already performed and there is no change in patient cancer status

Trial design

Treatments tested in this trial

  • Comprehensive Genomic Profile testing; ELIA software; Molecular Genetic Pathologist consultation
  • limited genetic testing or no testing

Treatment groups

300 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Bien-Willner Physicians Group PA

Lead sponsor

No One Left Alone

Collaborator

Carolina Blood and Cancer Care Associates

Collaborator