Monitoring and Early Response Evaluation Using HPV DNA - A Study on Patients With HPV-positive Throat Cancer (MER-HPV)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorRegion Skane

About this trial

The goal of this clinical trial is to determine the value of circulating tumour HPV DNA (human papilloma virus DNA found in the blood) at diagnosis, during treatment, and in the follow-up of patients diagnosed and treated for throat cancer caused by HPV.

The main question to answer is if the presence of HPV DNA in the blood one month after the treatment is useful in detecting remaining tumour or relapse within two years after treatment.

The participants will be asked to provide blood tests:

1. before treatment 2. weekly during the treatment 3. on all scheduled follow-up appointments 4. on all unplanned appointments where a relapse is suspected

Eligibility criteria

Qualifiers

Only patients with an HPV-positive primary tumour will eventually be eligible for inclusion.

Age >18 years.

Able to give informed consent.

The patient will be treated with curative intent.

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Blood sample

Treatment groups

150 Participants
are divided into 1 treatment group

Sponsors and collaborators