Morphology of Advanced Symptomatic Cerebral Plaques With High Embolic Potential
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age30-85
SponsorChinese University of Hong Kong
About this trial
The study is to attain early recognition of the unstable plaques which have an imminent embolic risk in patients with intracranial atherosclerotic disease (IAD).
Eligibility criteria
Qualifiers
Patient is 30 to 85 years of age, inclusive.
Patients who have an acute infarct in diffusion-weighted MRI compatible with artery-to-artery thrombo-embolism, a relevant intracranial atherosclerotic stenosis ≥60%, and MES detected by TCD.
Patient who has no contra-indication for the proposed imaging tests.
Patient understands the purpose and requirements of the study, and has provided an informed consent.
Disqualifiers
Stroke etiology uncertain or unrelated to intracranial atherosclerosis, such as cardioembolism, Moyamoya disease, small vessel disease, etc.
A tandem stenosis >50% at proximal internal carotid artery.
Bleeding propensity: active peptic ulcer disease, major systemic hemorrhage within 30 days, thrombocytopenia (platelets <100 x 109/L), coagulopathy (INR >1.5).
A medical condition that would not allow the patient to adhere to the protocol or complete the study.
Trial design
Treatments tested in this trial
- DSA/3DRA
Treatment groups
140 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov