Motor-Cognitive Interactive Upper Limb Robot Rehabilitation for Post-Stroke Motor Dysfunction

ConditionStroke
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-80
SponsorLidian Chen

About this trial

This study aims to investigate the effects of motor-cognitive interactive robot-assisted training on improving upper limb motor dysfunction after stroke. By observing different combinations of motor and cognitive components in the training, the study will clarify the relationship between the proportion of motor and cognitive elements and the recovery of upper limb motor function. The goal is to optimize the training protocol for upper limb rehabilitation robots and enhance their therapeutic outcomes.

Participants will be randomly assigned to one of three groups: motor-cognitive interactive robot-assisted training, motor-focused robot-assisted training, or conventional rehabilitation training. Training sessions will last 60 minutes, occur 5 times per week, and continue for 4 weeks. Researchers will measure changes in upper limb function and monitor for any adverse events during the training.

Eligibility criteria

Qualifiers

Diagnosis of stroke confirmed by CT or MRI.

Age between 40 and 80 years, with no gender restrictions.

First-ever stroke with unilateral limb paralysis.

Onset of stroke between 2 weeks and 6 months prior, with an FMA-UE score of 8-44.

Disqualifiers

History of neuromuscular diseases, malignant tumors, or other severe uncontrolled conditions, including cardiac, renal, or hepatic diseases.

Seated balance score < 2, or inability to maintain a sitting position for more than 60 minutes.

Modified Ashworth Scale score > 2.

Visual Analog Scale (VAS) score > 3 for hemiplegic shoulder pain.

Trial design

Treatments tested in this trial

  • Motor-cognitive interactive robot
  • Motor-focused robot
  • Conventional rehabilitation training

Treatment groups

1,047 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Lidian Chen

Lead sponsor

Fujian University of Traditional Chinese Medicine

Sponsor institution

Fujian University of Traditional Chinese Medicine Affiliated Rehabilitation Hospital

Collaborator

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Collaborator

China Rehabilitation Research Center

Collaborator

Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China

Collaborator

Shanghai Sunshine Rehabilitation Center

Collaborator