About this trial
The primary purpose of this interventional study is to examine the overall motor learning capacity from exposure to repeated perturbations among ambulatory people with multiple sclerosis (MS). This project will advance our understanding of learning new motor skills from exposure to external perturbations. If it is proven that people with MS can learn motor skills from perturbation training, the findings from this study will pave a theoretical foundation for applying perturbation training as a promising fall prevention intervention for people with MS.
Eligibility criteria
Qualifiers
Clinically confirmed multiple sclerosis
At least 45 years old
Able to walk independently at least 25 feet
Able to stand independently for at least 30 seconds
Disqualifiers
Previous experience with perturbation training
T-score from the dual x-ray absorptiometry (DXA) scan of less than -2.5
Coexisting psychiatric disorders or other neurological conditions, severe medical illness, or cardiovascular diseases
Participants have had a relapse in the past 8 weeks
Trial design
Treatments tested in this trial
- Perturbation Training
- Treadmill Walking
Treatment groups
Sponsors and collaborators
Georgia State University
Lead sponsor
National Multiple Sclerosis Society
Collaborator