Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorVA Office of Research and Development

About this trial

Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost of over $250 million. Among ambulatory people with chronic stroke (PwCS), impaired balance is a common health concern that substantially limits mobility (those with the worst balance walk the least). This project will explore adaptive strategies employed by PwCS in balance challenging environments and if a novel gait training intervention using a robotic device to amplify a person's self-generated movements can improve walking balance. The development of effective interventions to increase walking balance among PwCS will positively impact Veterans' health, quality of life, and ability to participate in walking activities.

Eligibility criteria

Qualifiers

History of chronic stroke (more than 6 months post-stroke) with weakness on one side

Ability to ambulate over ground for 10 meters with or without a single cane, and/or ankle-foot orthosis

Ability to tolerate 10 minutes of standing

Disqualifiers

Presence of cognitive impairment (score of 22/30 on the Montreal Cognitive Assessment scale (MoCA))

Presence of aphasia (score of 71/100 on the Mississippi Aphasia Screening Test (MAST))

Excessive spasticity in lower limbs (score of > 3 on the Modified Ashworth Scale

Severe cardiovascular and pulmonary disease affecting gait and balance

Trial design

Treatments tested in this trial

  • High intensity gait training in varying external environments
  • Treadmill walking in varying external environments

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators

VA Office of Research and Development

Lead sponsor

Northwestern University

Collaborator