About this trial
The goal of this case series study is to learn if magnetic resonance imaging (MRI) can show how well the palate and throat muscles work at rest and during speech after late cleft palate repair. The surgery uses a technique in which the muscle from the cheek is used to close the gap and repair the cleft and therefore improve speech. The study will answer the question of whether this technique will provide better closure and improved speech in the participants who have not received early treatment. The participants will have the surgery and then have MRI scans 6 months after surgery while resting and speaking specific sounds. Complete speech assessments will also be done 6 months after surgery.
Eligibility criteria
Qualifiers
Non-syndromic cleft palate (La Veau I-IV)
No prior palatal surgery
Consent for MRI and follow-up
Disqualifiers
Syndromic clefts or associated craniofacial anomalies.
Systemic co-morbidities
Previous palatal surgery.
Contraindications to MRI.
Trial design
Treatments tested in this trial
- Modified Furlow Palatoplasty combined with buccinator myomucosal flap
Treatment groups
Sponsors and collaborators
Cairo University
Lead sponsor
NewGiza University
Collaborator