MRI-Based Prediction of Dienogest Response in Endometriosis
ConditionEndometriosis, Ovarian
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age19-45
SponsorChungnam National University Sejong Hospital
About this trial
The goal of this prospective observational study is to learn whether magnetic resonance imaging (MRI) findings can help predict treatment response to dienogest in women with endometriosis. Endometriosis is a common gynecologic condition that can cause chronic pelvic pain and negatively affect quality of life. Although dienogest is widely used as a standard medical treatment, individual responses to treatment vary.
The main questions this study aims to answer are:
* Whether baseline MRI characteristics of endometriotic lesions are associated with improvement in pelvic pain after dienogest treatment. * Whether MRI findings can help identify patients who are more likely to benefit from dienogest therapy.
Participants diagnosed with endometriosis who are prescribed dienogest as part of their routine clinical care will be enrolled. This study does not assign any investigational intervention. Participants will undergo standard clinical follow-up, including pelvic pain assessment using visual analog scale (VAS) scores, quality of life questionnaires, and routine MRI examinations. Clinical and imaging data will be collected prospectively and analyzed to explore imaging predictors of treatment response.
Eligibility criteria
Qualifiers
Female participants who have received a full explanation of the study and have provided written informed consent
Women aged 19 to 45 years who have been diagnosed with endometriosis by a board-certified obstetrician-gynecologist
Patients who have not received any hormonal treatment within the previous 3 months
Patients who have never been treated with dienogest
Disqualifiers
Patients with a history of treatment with dienogest
Patients with contraindications to dienogest
Patients who are unable to undergo magnetic resonance imaging (MRI) (e.g., presence of metallic implants)
Patients who are currently pregnant or planning pregnancy within the next 6 months
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Source ClinicalTrials.gov