MRI-Eye Tracking Pairing, a Tool for Assessing Social Cognition in Children With ASD

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age10-20
SponsorCentre Hospitalier Universitaire, Amiens

About this trial

Most studies use static visual percepts that are less representative of joint attention versus an ecological environment. This has the consequence of decreasing the perception of an interaction with a social partner, which is an essential step in achieving joint attention. The originality of this study is to improve the design of visual percepts (in the form of video) in order to mimic an ecological environment as much as possible by using MRI-ET coupling. The second originality of this study is the longitudinal exploration of the neurodevelopment of social cognition in autistic children. Studies by the Redcay and Oberwelland teams observe different activations at different ages. The hypothesis is that the perception of joint attention varies over time in people with ASD. To date, there are no studies to determine the influence of childhood neurodevelopment in autistic people on the perception of joint attention. It would be unprecedented to use the MRI-ET pairing as a tool for assessing social cognition as a function of the development of children with ASD.

Eligibility criteria

Qualifiers

Age between 10 to 20 years old

Diagnosis of ASD (CARS) ≥ 30 performed at inclusion

IQ test evaluation (regardless of the result) performed by a trained psychologist

Obtaining informed oral and written consent after appropriate information

Disqualifiers

Age outside the range 10 to 20 years

Person with a contraindication to MRI (including claustrophobia, pace maker, neurosurgical clips, vascular clips, heart valves, ventriculoperitoneal valves, cochlear implant, neurostimulator, intraocular metal shards, joint prosthesis, etc.)

Person suffering from major obesity (> 140 kg) not allowing him to enter the tunnel of the MRI machine (diameter <70cm)

Pregnant or breastfeeding woman

Trial design

Treatments tested in this trial

  • MRI-ET

Treatment groups

68 Participants
are divided into 2 treatment groups