MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorDuke University

About this trial

The purpose of this research study is to understand how healthy individuals self-regulate motivation by observing brain activity using magnetic resonance imaging (MRI).

Eligibility criteria

Qualifiers

Age between 18 and 45 years

Male or female

Right-handed

In good general health

Disqualifiers

Current or diagnosis within past six months of an DSM-V Axis I or Axis II disorder (self-reported)

CES-D score of 20 or higher (indicating significant current depression symptoms)

Current or past six month use of prescription medications indicated for psychiatric conditions (e.g.,depression, anxiety)

Current serious medical illness (self-reported)

Trial design

Treatments tested in this trial

  • Ventral tegmental area of dopaminergic midbrain (VTA) fMRI neurofeedback

Treatment groups

190 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Duke University

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator