Multi Center Observation of Sentinel Skin Graft for Detecting Acute Rejection After Renal Transplantation

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

About this trial

The purpose of this study was to explore the accuracy of sentinel skin grafts from the same donor source in diagnosing renal allograft rejection, and to provide new ideas and options for the later clinical diagnosis of renal allograft rejection. Further, try to provide timing guidance for early immunization intervention.

Eligibility criteria

Qualifiers

Patients with end-stage renal disease undergoing renal transplantation;

18-60 years old;

Postoperative follow-up points are complete (visit the hospital every week in the first month after surgery, every two weeks in 2-3 months, every four to six months, and every three months in 7-12 months. Follow up at any time when skin rejection is observed. The follow-up time may be adjusted when the condition changes);

The participants had good compliance, volunteered to participate in the test and signed the informed consent form.

Disqualifiers

Untreated or disseminated malignant tumor;

Active period of infectious diseases;

Serious cardiovascular disease occurred recently;

Combined with other important organ failure;

Trial design

Treatments tested in this trial

  • Skin allotransplantation

Treatment groups

24 Participants
are divided into 1 treatment group

Sponsors and collaborators

Second Affiliated Hospital, School of Medicine, Zhejiang University

Lead sponsor

Zhejiang University

Collaborator

Sir Run Run Shaw Hospital

Collaborator

The First Affiliated Hospital of Air Force Medicial University

Collaborator