Multi-center Screening for Serum M Protein
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age30+
SponsorZhujiang Hospital
About this trial
This study aims to utilize a highly sensitive method for detecting M protein in serum to examine the prevalence of M protein in various age groups of individuals aged over 30 who underwent physical examinations in different regions of China. Furthermore, the study seeks to analyze the relationship between physical examination indicators and the presence of serum M protein (as measured by relative intensity) in the study participants at the time of enrollment. Additionally, a 5-year follow-up period will be employed to observe the association between annual physical examination indicators and clinical outcomes in subjects identified with positive/negative serum M protein screening.
Eligibility criteria
Qualifiers
Over 30 years old.
Volunteer to participate in this study and sign an informed consent form.
According to previous studies, a positive rate of 5% -8% was found in subjects with positive M protein screening. Each sub center included approximately 50-80 positive subjects based on actual conditions. At the same time, control subjects with negative M protein testing were matched by age and gender parameter 1:1.
Volunteer to participate in the follow-up phase of the study and sign an informed consent form.
Disqualifiers
Samples with incomplete or untraceable subject data.
Unqualified samples: including serum samples with severe hemolysis, fatty blood or jaundice, insufficient sample, and samples not stored as required.
The subject requested to withdraw from the study midway.
Duplicate samples of subjects at the same time point.
Trial design
Treatments tested in this trial
- Serum M protein screening
Treatment groups
10,000 Participants
are divided into 3 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov