Multi-Disciplinary Treatment on the Anthropomorphism of Large Language Models

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorNorth Sichuan Medical College

About this trial

This retrospective clinical trial aims to better explore the potential of large language models in medicine by comparing the effectiveness of MDT consultations conducted by human doctors with those conducted by large language models.

The main questions to be addressed are:

Does using large language models to conduct anthropomorphic MDT consultations yield better results than using non-anthropomorphic processes? Is there a significant performance gap between MDT consultations conducted by large language models and those conducted by humans? How much greater is the economic benefit of MDT consultations from large language models compared to those conducted by humans?

Retrospectively collect MDT consultation records from the past 20 years in northern Sichuan in China, as well as anonymized patient medical records. Group 1: Different large language models are assigned to act as doctors from different departments and as MDT secretaries to summarize consultations. Group 2: The large language model directly outputs diagnostic and treatment recommendations for patients. Compare the outputs of groups 1 and 2 with human performance retrospectively, score them, and select the best model from each department for a re-evaluation through anthropomorphic MDT consultations, once again comparing them to human results.

Eligibility criteria

Qualifiers

1. The medical records include interdisciplinary consultation notes, with recommendations from specialists of various departments and a well-documented final summary.

2. The medical records contain data from at least one year prior to and one year following the consultation (including intact reports and imaging records).

3. The patient's discharge conditions improved due to the multidisciplinary treatment plan after the consultation.

Disqualifiers

1. The medical records do not include multidisciplinary consultation notes, or the recommendations from various departmental physicians and the final summary notes are incomplete or inadequate.

2. The medical records lack data from 1 year before and after the consultation, or miss necessary reports and imaging data, resulting in incomplete documentation.

3. The patient's condition at discharge has not improved following the multidisciplinary treatment plan, or the condition has worsened.

Trial design

Treatments tested in this trial

  • GPT-4o
  • GPT-4o mini
  • MedicalGPT
  • Claude-3.5 Sonnet
  • Claude 3 Haiku
  • Real Doctors

Treatment groups

300 Participants
are divided into 4 treatment groups

Sponsors and collaborators

North Sichuan Medical College

Lead sponsor

Affiliated Hospital of North Sichuan Medical College

Collaborator

University of Glasgow

Collaborator

Peking University

Collaborator

Peking University First Hospital

Collaborator

Beijing Institute of Petrochemical Technology

Collaborator

Case Western Reserve University

Collaborator

Monash University

Collaborator