About this trial
The purpose of this study is to examine the benefits of combining repetitive Transcranial Magnetic Stimulation (rTMS) coupled with Cognitive Processing Therapy (CPT) in treating combat-related Posttraumatic Stress Disorder (PTSD) symptoms. The study will also examine change in depression, psychosocial functioning, and neurophysiological (i.e., electroencephalography and magnetic resonance images) measures.
Eligibility criteria
Qualifiers
Veterans of Post-9/11 military conflicts
with diagnosis of PTSD based on CAPS-5 related to Post-9/11 military combat
Disqualifiers
current enrollment in an acute experimental treatment for PTSD or trauma-focused psychotherapy treatment
PTSD-inducing trauma exposure occurring within the last 3 months prior to pre-enrollment evaluation
history of epilepsy or seizure disorder, a history of major head trauma,
any neurologic condition likely to increase risk of seizures,
Trial design
Treatments tested in this trial
- Active rTMS
- Sham rTMS
- Cognitive Processing Therapy
Treatment groups
Sponsors and collaborators
The University of Texas at Dallas
Lead sponsor
University of Texas Southwestern Medical Center
Collaborator
Johns Hopkins University
Collaborator
Metrocare Services of Dallas
Collaborator
Florida State University
Collaborator