About this trial
To study the optimal therapeutic strategies for salvage treatment of refractory/relapsed AML, and to clarify the effectiveness and safety of various salvage treatment options. A prospective, multicenter, platform-type study was conducted to explore the overall response rate, tolerability, and survival of patients with R/R AML with different treatment regimens.
Eligibility criteria
Qualifiers
1. Patients with acute myeloid leukemia (except for acute promyelocytic leukemia) diagnosed by bone marrow cell morphology, immunology and genetics above are classified according to the French-British-American Collaboration diagnostic criteria (FAB criteria) and the World Health Organization diagnostic criteria (WHO2016 criteria).
Disqualifiers
Concurrent malignant tumors of other organs (patients requiring treatment).
Participants considered unsuitable for inclusion by the researchers.
Trial design
Treatments tested in this trial
- Ivosidenib,Venetoclax,gilteritinib,Selinexor
Treatment groups
7
Treatment groupsSee each treatment group below.