Multicenter Study on Postoperative Urinary and Sexual Function During Laparoscopic Functional Total Mesorectum Excision

ConditionRectal Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18-70
SponsorRenmin Hospital of Wuhan University

About this trial

Urinary and sexual dysfunctions are among the most common complications in rectal cancer surgery. The aim of this study was to investigate the protective effect of laparoscopic functional total mesorectum excision (FTME) on urinary and sexual function in male patients with mid-low rectal cancer. This is a prospective, single-arm, multicenter, uncontrolled, clinical study in 88 eligible subjects with mid-low rectal cancer. After informed consent, eligible patients will be performed laparoscopic FTME surgery. Patients' demographic, operative detail, postoperative outcomes and follow-up will be recorded prospectively.

Eligibility criteria

Qualifiers

Male, 18-70 years of age, informed consent;

Tumors from anal edge 6 ~ 12 cm (measured by rigid proctoscope);

Rectal cancer confirmed pathologically by endoscopic biopsy;

Preoperative cT1-3aN0M0 stage (ESMO, 2013);

Disqualifiers

History of abdominal and pelvic major surgery;

Emergency surgery is needed due to the complication (bleeding, obstruction, or perforation) caused by rectal cancer;

Pelvic or distant metastasis;

Neoadjuvant radiotherapy or chemoradiotherapy;

Trial design

Treatments tested in this trial

  • Laparoscopic FTME surgery

Treatment groups

88 Participants
are divided into 1 treatment group