Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital Muenster

About this trial

Primary objectives: Primary objectives are to assess and define benchmarks of the surgical outcome in the form of extent of resection, functionality, and quality of life after resection of juxta medullary tumors Secondary objectives: Assessment of variables leading to better outcome through regression analysis: 1. Influence of surgical approach on functionality, pain, and quality of life 2. Comparison between patient with severe neurological (McCormick scale 3-5) to patients with mild deficits (McCormick scale 1-2) 3. Role of intraoperative monitoring (IOM) in extent of resection and neurological deficits Assessment of treatment variations: 1. Assessment of risk factors for incomplete resection 2. Non inferiority of unilateral approach to achieve gross total resection of spinal meningioma, schwannoma and cauda ependymoma 3. Role of bed rest after surgery to prevent cerebro-spinal fluid leakage 4. Influence of laminectomy on cerebro-spinal fluid leakage Quality indicators: assessments of length of hospital stay, 30- and 90-days re-admissions, 30- and 90-days re-surgery, nosocomial infections

Eligibility criteria

Qualifiers

Adult, age ≥18 years, patients treated on intraspinal, extra medullary tumor

Patients must have sufficient cognitive and language skills to give informed consent

Disqualifiers

Absence of informed consent

Lack of ability to consent

Primary bone tumors invading the intra-spinal space

Vertebral metastasis

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators

University Hospital Muenster

Lead sponsor

Technical University of Munich

Collaborator

University Hospital Freiburg

Collaborator

Medical University of Cologne

Collaborator

Universitätsklinikum Hamburg-Eppendorf

Collaborator