About this trial
The goal of this clinical trial is to evaluate the clinical effects of ultra-fast-track anesthesia (UFTA) for minimally invasive cardiac surgery (MICS) in adults. It will also learn about the safety and feasibility of Ultra-Fast-Track cardiac surgery(UFTCA).The main questions it aims to answer are:Does UFTCA promote rapid postoperative recovery, reduce postoperative complications and perioperative mortality, and improve the quality of mid- and long-term survival.And does it improve patient satisfaction and reduce healthcare costs.
Participants will receive homogenized perioperative management in the cardiac ward, extracorporeal circulation, and postoperative ICU, except for anesthesia extubation time.Furthermore,Participants need complete quality of life scales at 30 days, 90 days, six months, and one year after surgery, separately.
Participants in this study are adults who required elective minimally invasive heart valve surgery under extracorporeal circulation.This study will be able to promote rapid recovery while reducing the associated costs and the financial burden on participants.Retrospective big data analysis of perioperative clinical characteristics of patients undergoing minimally invasive heart valve surgery to establish a risk warning model and develop a perioperative management program. The investigators then conducts a randomized group trial comparing the similarities and differences between conventional general anesthesia(CGA) and ultra-fast-track cardiac anesthesia(URTCA) to demonstrate the effectiveness and safety of UFTA in MICS.Finally, building expert consensus.
Eligibility criteria
Qualifiers
Age ≥18 and ≤80 years
American Society of Anaesthesiologists (ASA) class I-III
New York Heart Association (NYHA) cardiac class III or below
Preoperative inspired air pulse oximetry (SpO2) ≥95%
Disqualifiers
Patient's refusal to participate
Severe communication disorders
Severe disorders of coagulation with spontaneous bleeding tendency
Long-term application of opioid analgesics
Trial design
Treatments tested in this trial
- Ultra-Fast-Track Cardiac Anesthesia(UFTCA)
- conventional general anesthesia (CGA)
Treatment groups
Locations
Sponsors and collaborators
Zhejiang Provincial People's Hospital
Lead sponsor
Beijing Anzhen Hospital
Collaborator
Fudan University
Collaborator
Wuhan Asia Heart Hospital
Collaborator
Tianjin Chest Hospital
Collaborator
Chinese PLA General Hospital
Collaborator
First Affiliated Hospital Xi'an Jiaotong University
Collaborator
Xiangya Hospital of Central South University
Collaborator
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Collaborator
Guangdong Provincial People's Hospital
Collaborator