Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMassachusetts General Hospital
About this trial
The goal of this study is to demonstrate the efficacy of a multidisciplinary group-based telehealth intervention (HORIZONS) compared to minimally enhanced usual care for improving self-management and quality of life for hematopoietic stem cell transplant (HSCT) survivors living with chronic graft-versus host disease, and to identify critical facilitators and barriers for HORIZONS implementation and adoption.
Eligibility criteria
Qualifiers
Adult patients (≥ 18 years) who have undergone allogeneic HCT
Have moderate to severe cGVHD based on patient-report
Have ability to participate in English or Spanish language group telehealth intervention.
Disqualifiers
Patients with mild cGVHD based on their self-report.
Patients with a major untreated psychiatric or cognitive condition which the treating oncology clinicians believes interferes with the capacity to provide informed consent.
Patients with active relapsed disease requiring therapy.
Trial design
Treatments tested in this trial
- HORIZONS Intervention
- Minimally enhanced usual care
Treatment groups
350 Participants
are divided into 2 treatment groupsSponsors and collaborators
Massachusetts General Hospital
Lead sponsor
University of Miami Sylvester Comprehensive Cancer Center
Collaborator
Source ClinicalTrials.gov