Multifaceted Comparison of Ultrasound-guided Ablation and Laparoscopic Adrenalectomy for Aldosterone-producing Adenoma

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThird Affiliated Hospital, Sun Yat-Sen University

About this trial

The purpose of this study is to retrospectively and prospectively analyze the efficacy and safety of ultrasound-guided radiofrequency ablation and laparoscopic adrenalectomy in the treatment of aldosterone-producing adenoma (APA). It is planned to retrospectively collect 30 patients with adrenal radiofrequency ablation for APA and 15 patients with age - and sex-matched laparoscopic adrenalectomy for APA in our hospital from January 2020 to June 2024, and continue to follow up for 3 years.

Eligibility criteria

Qualifiers

APA was confirmed with unilateral lesions;

Benign tumor without adrenal metastasis and endovascular tumor embolus;

Receive ultrasound-guided adrenal RFA treatment or laparoscopic resection, and sign the informed consent for surgery;

Age ≥ 18;

Disqualifiers

Bilateral adrenal diseases;

Multiple adrenal tumors;

Other adrenal diseases, such as adrenal hyperplasia, Cushing's syndrome, pheochromocytoma, etc.;

Imaging suggests that the tumor may be difficult to reach;

Trial design

Treatments tested in this trial

  • radiofrequency ablation
  • laparoscopic adrenalectomy
  • Hypotensive Drugs

Treatment groups

45 Participants
are divided into 2 treatment groups