About this trial
PTC(Pseudotumor cerebri) patients may develop increased Intracranial pressure (ICP) that can produces increased pressure around the distal optic nerve,which is likely followed by venule compression, ischemia, and loss of visual function.Vision loss in PTC is most commonly characterized by standard automated perimetry to measure peripheral visual field sensitivity.
Pupillometry is a promising approach for functional assessment in PTC because it is noninvasive, objective, performed quickly with minimal patient cooperation needed.
The feasibility of using chromatic multifocal pupillometry for assesment of PTC will be examined.
Eligibility criteria
Qualifiers
Male or female patients, age between 18 and 80 years, inclusive
Informed written consent will be obtained from all participants.
Normal eye examination
Best-corrected visual acuity (BCVA) of 20/20
Disqualifiers
History of past (last 3 months) or present ocular disease or ocular surgery
Use of any topical or systemic medications that could adversely influence pupillary reflex
Intolerance to gonioscopy, slit lamp examination, Goldmann applanation tonometry or other schedule study procedure.
Mental impairment or instability such as that informed consent may not be obtained or compliance with tester instructions is unlikely.
Trial design
Treatments tested in this trial
- objective chromatic multifocal pupillometer