The purpose of this clinical trial is to understand the effectiveness of femoral nerve block, combined sciatic and femoral nerve block, lumbar plexus block, epidural block, and intravenous analgesia pump in the application of lower limb injury (total knee replacement, knee arthroscopy, patella fracture, femoral shaft fracture) surgery. It will also understand the safety of the drugs liposomal bupivacaine and ropivacaine. The main question it aims to answer is: Does nerve block reduce the number of times participants need to use analgesics postoperatively? The researchers will compare femoral nerve block, combined sciatic and femoral nerve block, lumbar plexus block, epidural block, and intravenous analgesia pump to see which analgesic method has the best postoperative analgesic effect. Participants will: undergo nerve block first, then endotracheal intubation general anesthesia after entering the operating room; record vital signs during surgery, record postoperative analgesic doses, NRS pain scores, patient satisfaction, and postoperative nausea and vomiting.
American Society of Anesthesiologists (ASA) physical status classification I-III
Patients (or their guardians) voluntarily participate in this study and sign a written informed consent form
Patients (or their guardians) are able to understand the study content and cooperate with the study protocol
Known allergy to local anesthetics or opioid analgesics.
Presence of contraindications to local or epidural anesthesia.
Presence of undiagnosed or poorly characterized neuropathic pain.
Presence of severe mental illness that would impede the participant's ability to cooperate with study assessment and treatment procedures.
Xiaguang Duan
Lead sponsor
Inner Mongolia Baogang Hospital
Sponsor institution