About this trial
Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications. Fascial plane blocks have emerged as part of multimodal analgesia strategies in cardiac surgery.
This prospective, randomized, controlled, single-blinded study aims to evaluate the effect of an induction-time multimodal fascial plane block package-consisting of bilateral superficial parasternal block, bilateral serratus anterior plane block, and adductor canal block-on postoperative analgesia, opioid consumption, and clinical outcomes in patients undergoing elective isolated CABG with saphenous vein graft harvesting.
Patients will be randomized in a 1:1 ratio to receive either the multimodal fascial plane block package in addition to standard postoperative analgesia or standard postoperative analgesia alone. The primary outcome is total opioid consumption within the first 24 postoperative hours. Secondary outcomes include pain scores, time to first opioid requirement, extubation time, postoperative pulmonary complications, atrial fibrillation, and length of ICU and hospital stay.
Eligibility criteria
Qualifiers
Age between 18 and 80 years
Scheduled for elective isolated coronary artery bypass grafting (CABG) with saphenous vein graft harvesting
ASA physical status II-IV
Ability to provide written informed consent
Disqualifiers
Known coagulopathy or contraindication to regional anesthesia
Use of anticoagulant therapy precluding regional block
Known allergy to local anesthetics
Local infection at planned block sites
Trial design
Treatments tested in this trial
- Multimodal Fascial Plane Block Package
- Standard Postoperative Analgesia
Treatment groups
Sponsors and collaborators
Saglik Bilimleri Universitesi
Lead sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Sponsor institution