Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorSaglik Bilimleri Universitesi

About this trial

Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications. Fascial plane blocks have emerged as part of multimodal analgesia strategies in cardiac surgery.

This prospective, randomized, controlled, single-blinded study aims to evaluate the effect of an induction-time multimodal fascial plane block package-consisting of bilateral superficial parasternal block, bilateral serratus anterior plane block, and adductor canal block-on postoperative analgesia, opioid consumption, and clinical outcomes in patients undergoing elective isolated CABG with saphenous vein graft harvesting.

Patients will be randomized in a 1:1 ratio to receive either the multimodal fascial plane block package in addition to standard postoperative analgesia or standard postoperative analgesia alone. The primary outcome is total opioid consumption within the first 24 postoperative hours. Secondary outcomes include pain scores, time to first opioid requirement, extubation time, postoperative pulmonary complications, atrial fibrillation, and length of ICU and hospital stay.

Eligibility criteria

Qualifiers

Age between 18 and 80 years

Scheduled for elective isolated coronary artery bypass grafting (CABG) with saphenous vein graft harvesting

ASA physical status II-IV

Ability to provide written informed consent

Disqualifiers

Known coagulopathy or contraindication to regional anesthesia

Use of anticoagulant therapy precluding regional block

Known allergy to local anesthetics

Local infection at planned block sites

Trial design

Treatments tested in this trial

  • Multimodal Fascial Plane Block Package
  • Standard Postoperative Analgesia

Treatment groups

56 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Saglik Bilimleri Universitesi

Lead sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Sponsor institution