Multimodal Musical Stimulation for Healthy Neurocognitive Aging

ConditionAging
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-95
SponsorNortheastern University

About this trial

This is a Stage I randomized, sham-controlled trial on the effects of multimodal musical stimulation on working memory in aging. Neurologically healthy older and younger adults will be tested on working memory and electroencephalography in the first randomized controlled trial of music as a form of brain stimulation, with multimodal musical stimulation and control stimulation conditions. Results will test the causal role of oscillatory mechanisms of the brain on cognition, and will lay the groundwork to the first musical, neurophysiologically targeted, brain-stimulation device for reversing cognitive decline in aging.

Eligibility criteria

Qualifiers

normal or corrected-to-normal vision

no more than mild hearing loss

no recent history of neurological or psychiatric disorders, including mood disorders or use of medications that may affect cognition or responsiveness to music.

Disqualifiers

moderate or severe hearing loss (40+ dB)

visual impairment (including color blindness) that cannot be corrected with glasses or contacts

recently changed dosage of cholinesterase inhibitors or psychotropic medication

recent history of psychotic or schizophrenic episodes

Trial design

Treatments tested in this trial

  • Gamma
  • Synchrony

Treatment groups

100 Participants
are divided into 2 treatment groups

Sponsors and collaborators