Multimodal Ophthalmic Imaging and Plasma Biomarkers for the Early Detection of Alzheimer's Disease

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50+
SponsorPeking University First Hospital

About this trial

With the accelerating global aging population, dementia has become a pressing worldwide issue. This project aims to identify specific plasma biomarkers and ocular indicators for the early detection of Alzheimer's disease (AD).

Eligibility criteria

Qualifiers

Male or female participants aged ≥ 50 years;

Participants diagnosed with Alzheimer's Disease (AD), mild cognitive decline (MCI), subjective cognitive decline (SCD), or cognitively normal (CN);

Signed informed consent form

Disqualifiers

Presence of other neurological disorders and systemic diseases that may cause cognitive impairment;

Inability to cooperate with cognitive assessments;

Refusal to undergo blood sampling.

Trial design

Treatments tested in this trial

  • Multimodal Ophthalmic Imaging and plasma biomarker

Treatment groups

200 Participants
are divided into 1 treatment group