Multimodal Prehabilitation for Surgery in the Elderly: a Randomised, Prospective, Multicenter, Multidisciplinary Trial

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorInsel Gruppe AG, University Hospital Bern

About this trial

This multicentric, randomised controlled trial is to the investigators knowledge the first implementation of a multimodal, multidisciplinary prehabilitation approach using knowledge from different specialties to lower complications and to increase cost effectiveness after major surgery in elderly, frail patients.

Eligibility criteria

Qualifiers

Written informed consent

comorbid (≥ASA 3)

pre-existing fitness deficit: AT<11ml/kg/min respectively VO2peak<14ml/kg/min if AT unavailable or VE/VCO2 slope > 33

scheduled for major urologic, thoracic, visceral, orthopaedic or cardiovascular surgery

Disqualifiers

Paralysis or patients with mobility problems (who are unable to exercise),

Premorbid conditions or orthopaedic impairments that contraindicate exercise,

Cognitive disabilities,

Chronic renal failure (need for dialysis)

Trial design

Treatments tested in this trial

  • Multimodal Prehabilitation

Treatment groups

466 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Insel Gruppe AG, University Hospital Bern

Lead sponsor

University of Bern

Collaborator

Department of clinical research, Bern

Collaborator