Multiomics Study of Biological Behavior of Lymph Node Metastasis in Papillary Thyroid Carcinoma
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorTianhan Zhou
About this trial
Establish a predictive model for assessing neck lymph node metastasis of papillary thyroid carcinoma based on metabolomics, proteomics, and imaging omics data, exploring an ideal protocal for the precise diagnosis and treatment of papillary thyroid carcinoma."
Eligibility criteria
Qualifiers
Pathological confirmation of PTC.
Patients who underwent primary surgery accompanied by central neck lymph node dissection.
Tumors measuring less than 2 cm in diameter.
Postoperative pathological reports including detailed information on the number of lymph nodes dissected and the number of metastatic lymph nodes.
Disqualifiers
Postoperative pathological diagnosis indicating sub-types of PTC.
Tumor invasion into adjacent anatomic structures such as the sternothyroid muscle, surrounding soft tissues, trachea, esophagus, or laryngeal nerve.
History of neck trauma, previous tumor surgery, or adjuvant chemoradiotherapy.
Fewer than three lymph nodes dissected during surgery.
Trial design
Treatments tested in this trial
- Thy_CLNM_multi_omics
Treatment groups
2,000 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Tianhan Zhou
Lead sponsor
Zhejiang Chinese Medical University
Sponsor institution
Source ClinicalTrials.gov