About this trial
This prospective observational study investigates using multiparametric magnetic resonance imaging (MRI) to improve the characterization and management of therapy for hepatocellular carcinoma (HCC). The goal is to evaluate whether advanced MRI parameters can support noninvasive diagnostic assessments and personalized treatment plans for patients with HCC. The study is being conducted at a single university center in Germany and includes adult patients with confirmed or suspected HCC. Participants will undergo standardized multiparametric MRI examinations, and the imaging data will be correlated with clinical, pathological, and therapeutic outcomes. No study-specific interventions or medications will be administered.
Eligibility criteria
Qualifiers
Age ≥18 years
Confirmed or suspected diagnosis of HCC
Scheduled to receive TACE or SIRT as part of standard clinical care
Eligibility for liver MRI
Disqualifiers
Contraindications to MRI (e.g., pacemakers, ferromagnetic implants, severe claustrophobia)
Known allergy or intolerance to gadolinium-based contrast agents
Renal insufficiency with estimated glomerular filtration rate (eGFR) <30 mL/min/1.73m²
Pregnancy or breastfeeding
Trial design
Treatments tested in this trial
- Multiparametric MRI