Multiparametric MRI for Characterization of Hepatocellular Carcinoma

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital Muenster

About this trial

This prospective observational study investigates using multiparametric magnetic resonance imaging (MRI) to improve the characterization and management of therapy for hepatocellular carcinoma (HCC). The goal is to evaluate whether advanced MRI parameters can support noninvasive diagnostic assessments and personalized treatment plans for patients with HCC. The study is being conducted at a single university center in Germany and includes adult patients with confirmed or suspected HCC. Participants will undergo standardized multiparametric MRI examinations, and the imaging data will be correlated with clinical, pathological, and therapeutic outcomes. No study-specific interventions or medications will be administered.

Eligibility criteria

Qualifiers

Age ≥18 years

Confirmed or suspected diagnosis of HCC

Scheduled to receive TACE or SIRT as part of standard clinical care

Eligibility for liver MRI

Disqualifiers

Contraindications to MRI (e.g., pacemakers, ferromagnetic implants, severe claustrophobia)

Known allergy or intolerance to gadolinium-based contrast agents

Renal insufficiency with estimated glomerular filtration rate (eGFR) <30 mL/min/1.73m²

Pregnancy or breastfeeding

Trial design

Treatments tested in this trial

  • Multiparametric MRI

Treatment groups

128 Participants
are divided into 1 treatment group

Sponsors and collaborators