Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentro Cardiologico Monzino

About this trial

This is a multicenter, observational prospective and retrospective study which aims are: 1) to compute a scoring model potentially predictive for the diagnosis of fibrosis by CMR in patients with MVP; 2) to identify specific features that may predispose to ≥ mild VAs or SCD in patients with MVP.

Eligibility criteria

Qualifiers

age ≥ 18 years

Echocardiographic diagnosis of mitral valve prolaspe, defined as a systolic displacement of one or both mitral leaflets ≥ 2 mm above the plane of the mitral valve annulus in long-axis views

Disqualifiers

age< 18 years

coexistence of other cardiomyopathies or other ≥ moderate valve diseases

scarce acoustic transthoracic echocardiographic window

usual contraindications for cardiac magnetic resonance

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

300 Participants
are grouped into 2 trial groups

Sponsors and collaborators

Centro Cardiologico Monzino

Lead sponsor

Humanitas Hospital, Italy

Collaborator

IRCCS Ospedale San Raffaele

Collaborator

Azienda Ulss 2 Marca Trevigiana

Collaborator